Marya Automatic Vial Filling Line 1-100ml GMP Validation Liquid Filling Machine

• Customization: Available
• After-sales Service: Engineers Available to Service Machinery Overseas, Free Spare Parts, Online Support,video Technical Support
• Certification: CE, FDA, GMP, ISO
• Model NO.: MY-1503
• Condition: New
• Customized: Customized
• Fill Range: 1-100ml
• Filling Principle: Peristaltic Pump Filling
• Machine Type: Liquid Filling Machine
• Main Material: Stainless Steel
• Voltage: 380V
• Warranty: 12 Months
• Transport Package: Plywood Export Wooden Case
• Specification: Volume: 1-100ml
• Trademark: Marya
• Origin: China
• Production Capacity: 15-20 Sets / Year

Product Description

Marya Automatic Vial Filling Line 1-100ml GMP Validation Liquid Filling Machine
 

Marya is one of the leading liquid Vial Filling Machine manufacturers, can provide a wide range of automatic vial filling production line machines for the pharmaceutical industry including vial filling capping machine, vial stoppering machine. Capable of handling vial sizes up to 100ml and speeds up to 36000 per hour. Our vial filling machine can meet any requirements you need.

The vial liquid filling line is composed of ultrasonic vial washing machine, dryer sterilizer, vial injectable filling machine, vial stoppering machine and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, depyrogenation, cooling, bottle unscrambling, (nitrogen pre-filling) filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, biopharmaceuticals, chemical pharmaceuticals, blood products etc.

Application Scenarios:

Aseptic injections: antibiotics, chemotherapeutic drugs, biological protein preparations and other aqueous formulations for vial filling and capping.

Freeze-drying preparations: linked with freeze dryers to realize full-process automation of filling → freeze-drying → stoppering → capping.

Oral liquid and health care products: filling and capping for traditional Chinese medicine oral liquids, probiotic liquids, collagen beverages.

Vaccine production: vial filling for inactivated vaccines, mRNA vaccines and other biological preparations;

CRO/CDMO: flexible small-batch production and process validation for clinical trial drugs.

Performance Features:
 

Regulatory Compliance & Technical Standards

•  
• Data Integrity & Automation
• Developed in accordance with GAMP 5 guidelines, it features a fully integrated control system with Audit Trail, Electronic Records, and Electronic Signature, designed to support compliance with US FDA 21 CFR Part 11.
• GMP-Compliant Engineering
• Designed and manufactured in alignment with EU GMP Annex 1 (Manufacture of Sterile Products) and relevant US FDA regulatory guidelines.
• Safety & Market Access
• Compliant with EU CE safety standards and all applicable directives.
•  

The whole aseptic vial liquid filling sealing production line meets new GMP requirements, and the cleaning effect meets the new Pharmacopoeia standards and requirements;

 

The whole injectable vial filling line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level;

 

Applicable specification: 1ml-100ml vial (as per user's requirement);

 

Production Capacity of pharmaceutical vial filling machine: 1000-36000BPH;

 

Number of filling head: 1-20, to be selected according to the output;

 

Filling Accuracy: ≤±1% (according to drug characteristics);

 

The vial liquid filling machine adopts various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;

 

Capping qualified rate: ≥99.9%;

 

Compact and simple structure, occupies less area;

 

Stable product performance, easy and reliable operation, beautiful appearance;

 

High degree of automation, few operators required;

 

Single row or double row filling;

 

The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good;

 

To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used;

 

Applicable for wide range of bottle specifications, and easy to replace mould;

 

The products can be customized according to customer's actual demand;

 

 

Technical Parameters:

Model	KGF4	KGF6	KGF8	KGF10	KGF12	KGF20	KGF24
Applicable specifications	2~30ml vialbottles
Filling heads	4	6	8	10	12	20	24
Production capacity	50-100bts/min	80-150bts/min	100-200bts/min	150-300bts/min	200-400bts/min	250-500bts/min	300-600bts/min
Stoppering qualification rate	>=99%
Laminar air cleanliness	100grade
Vacuum pumping speed	10m3/h	30m3/h	50m3/h	60m3/h	60m3/h	100m3/h	120m3/h
Power consumption	5kw
Power supply	380V50Hz

Optional Systems :

Optional real-time display and printing system of sterilization temperature;

 

Optional online sterilization function for the cooling section of hot air circulation tunnel oven;

 

Optional open-RABS isolation protection system and class 100 laminar flow hood protection;

 

Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;

 

The capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution;

 

This pharma filling machine can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.;

 

Full-line linkage control function.

 

Company Profile

Workshop

Certificate

Project case

Our Customer

Exhibition & Our Team

Packaging & Shipping