Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System
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Product Highlights
- Full-Process Aseptic Closed-Loop: Eliminates secondary contamination with isolated closed filling design and automatic rejection of non-conforming products.
- GMP Validation Compliance: Meets GMP requirements with full traceability, automatic report generation for IQ, OQ, and PQ validation.
- Flexible Modular Design: Supports rapid changeover between syringe sizes and liquids, enabling CIP/SIP and easy maintenance.
- Intelligent HMI Control System: PLC-based touch-screen control with real-time monitoring, parameter storage, and fault alarm functions.
- Comprehensive After-Sales Service: Includes field installation, commissioning, training, and a 1-year warranty coverage.
Product Attributes
- Customization
- Available
- After-sales Service
- Field Installation, Commissioning and Training
- Warranty
- 1 Year Warranty
- Model NO.
- MY-1897
- Type
- Piston Filling Machine
- Automatic Grade
- Automatic
- Material Type
- Liquid
- Filling Valve Head
- Multi-Head
- Feed Cylinder Structure
- Multi-Room Feeding
- Dosing Device
- Capacity Cup
- Filling Principle
- Vacuum
- Packaging Container Lifting Structure
- Pneumatic Lifting
- Structure
- Linear
- Packaging
- Bottle
- Packaging Material
- Plastic
- Size
- Max 150*115*50, Min 55*30*15mm
- Machine Size
- 3500*1500*1800mm
- Transport Package
- Standard Export Package
- Specification
- Standard/Customized
- Trademark
- Marya
- Origin
- China
- Production Capacity
- 10000PCS/Month
- Package Size
- 350.00cm * 150.00cm * 180.00cm
- Package Gross Weight
- 3500.000kg
Shipping
- Shipping Cost:
- Contact the supplier about freight and estimated delivery time.
Online Trading Protection
- Payment Guarantee
-
Platform-protected payments with refund support for eligible order issues.
- Platform Logistics
- Clearer shipment tracking with platform-supported logistics.
- Inspection Service
- Optional pre-shipment inspection for quality and quantity checks.
- After-Sales & Dispute Handling
- Platform-assisted dispute resolution, including refunds or returns when applicable.
Only orders placed and paid through Made-in-China.com Secured Trading are eligible for payment protection and the corresponding platform services.
Product Images of Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System
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Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System -
Marya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System
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Product Description
eMarya Automatic 1ml Gel Prefilled Vaccine Sterile Syringe Filling Stoppering Machine with Isolation System
The syringe filling machine is specially designed for pre-filled syringes (PFS). Equipped with PLC touch-screen control, the machine enables easy parameter setting with fault alarm function. Modular structure facilitates format change-over and commissioning. It can work standalone or connect to complete aseptic production lines. It is suitable for mass production of pre-filled products in pharmaceutical, biotech and medical-aesthetic industries.
Application
This filling line is widely used in core fields such as pharmaceutical manufacturing and medical consumable production. It is particularly suitable for manufacturers of prefilled plastic syringes and disposable catheter flushers. The line can be employed for filling products that demand extremely high aseptic conditions, including clinical catheter flush solutions, vaccines, biological products, and aesthetic skin booster injections.
Features
1. Compliance & Traceability: Meets GMP Validation Requirements
- The machine is equipped with a PLC-based intelligent control system, enabling real-time monitoring and full traceability of all production parameters, including cleanliness, flushing pressure, and filling volume. It can automatically generate production reports, assisting enterprises in completing the full validation process of IQ (Installation Qualification), OQ (Operational Qualification), and PQ (Performance Qualification). This helps ensure successful compliance with pharmaceutical industry regulations and mitigates production compliance risks.
- The machine features a modular design with a compact structure, facilitating CIP (Clean-in-Place) and SIP (Sterilize-in-Place). It supports the production of various pharmaceutical liquids such as vaccines, biological products, and sterile flush solutions. The machine allows quick changeover between different models of syringes/catheters, meeting the requirements of pharmaceutical enterprises for large-scale, standardized aseptic production. We uphold the essential standards of aseptic compliance, improve production efficiency, reduce operational and maintenance costs, assist manufacturers in producing high-quality sterile medical consumables that meet industry standards, and strengthen their core market competitiveness.
2. Full-Process Aseptic Closed-Loop: Eliminates Secondary Contamination
- Aseptic Filling: The system adopts an isolated closed filling design, ensuring no exposure during liquid transfer. Equipped with a rotary ceramic pump and servo control system, the filling accuracy is controlled within ±1%. It is compatible with prefilled syringes of various volumes ranging from 0.1 to 20 mL, minimizing liquid waste and dosage deviation.
- Integrated Automatic Operation: The machine integrates filling, stoppering, and sealing into a fully automated process with no manual intervention. An online seal integrity detection system ensures leak detection accuracy ≤ 0.01 mL, and non-conforming products are automatically rejected, ensuring that every finished product meets aseptic standards.
- Flexible Adaptability: The modular design offers a compact structure, easy cleaning, maintenance, and upgrade. It supports rapid changeover between different sizes of catheters and multiple types of liquid (e.g., vaccines, insulin, sodium chloride flush solution). Parameters can be customized according to enterprise requirements, accommodating both large-scale batch production and small-batch custom orders.
3. Intelligent Control
- Equipped with an intuitive human-machine interface (HMI), the system enables real-time monitoring of equipment operating status, aseptic environmental parameters, and filling accuracy. Parameters can be stored and retrieved, ensuring full production traceability, facilitating quality control and compliance audits, and reducing operational, maintenance, and training costs.
4. Material Compliance: Meets Medical-Grade Biocompatibility Standards
- All components that come into contact with the liquid are made of medical-grade stainless steel 316L (in compliance with GB/T 1220-2019), with a surface roughness Ra ≤ 0.4 μm. The surfaces are electropolished to provide resistance to acids, alkalis, and chemical corrosion, with no leaching of harmful substances. The materials are validated to ISO 10993 for biocompatibility of medical devices, eliminating the risk of liquid contamination originating from the material itself, thereby meeting the strict material compliance requirements for the production of sterile medical consumables.
Product Parameters
| Filling Range | 0.1ml-20ml |
| Filling Mode | Customized (metal pump, peristaltic pump, ceramic pump) |
| Filling Accuracy | ±1% |
| Silicone Oil Spraying Accuracy | 0.5mg-2mg |
| Production Capacity | 2000-30000 pcs/hour |
| Pass Rate | ≥99.5% |
| Equipment Noise | ≤70db |
| Power Supply and Power Rating | 380V 50HZ |
About the Supplier
This supplier has been audited by TÜV Rheinland. Verify the report on the official TÜV Rheinland website with ID "MIC-ASR2542074". Items marked "
" are certified.
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Company Profile
Marya is a professional aseptic filling line manufacturer with turnkey solutions. With 12 years of industry experience, we have independently developed a comprehensive range of filling lines, including cartridge, vial, and pre-filled syringe (PFS) filling lines. In addition, we offer self-developed supporting equipment such as isolators/RABS, solution preparation systems, and water treatment systems, and VHP sterilizers. Our capabilities also extend to providing turnkey solutions for cleanroom projects and complete filling production lines. We have expanded business to over 70 countries worldwide, serving clients covering European, American and other mainstream markets, including renowned pharmaceutical enterprises and official governmental institutions. Centered around professional filling line technology, we are committed to delivering aseptic production lines and solutions that are stable, compliant, and efficient.
Five Things You Should Know About Marya
1 Engineering design
Our experienced engineering team with more than 20 years experience in pharmaceutical production plants, can ensure that process and equipment for your plant is designed and manufactured in the most cost-effective manner with reliable quality to fulfil GMP/FDA/ISO/SGS requirement.
2 Manufacturing Plants
Marya's 3 manufacturing plants for clean room walls, windows, doors and pharmaceutical machinery are all under strict quality management systems certified to ISO 9001 with a focus on continuous quality improvement.
3 Installation & Commissioning
Experienced, professional, high-efficiency and strictly stick to the schedule, our installation engineers and workers team has successfully installed more than 300+ projects in oversea with high customer satisfaction.
4 Proven Experience
Since 2014, Marya has maintained good cooperation relationship with Novartis, US pharma, MSD, NBA (Zimbabwe National Biotechnology Administration), Novo Nordisk, Techno drugs and other internationally renowned top pharmaceutical companies and national government agencies for a long time. So far, we have assisted famous pharmaceutical factories or government agencies in more than 70+ countries of 6 continents including the United States, Britain, Australia, Malaysia, Argentina and Tanzania to build high-grade cleanroom and aseptic preparation filling production lines that meet local requirements and GMP or FDA standards, winning a very good reputation.
5 Continuous Technical Support
Whatever you buy from us, No matter when your project finished, we will provide continuous service on the operation, maintenance, repairing, spare parts supplying improving and upgrading.
About Our Factory & Business Background
-
Business Type
- Manufacturer/Factory & Trading Company
- Address
- No211, North Fute Road, Pudong Area, 200131, Shanghai, China
-
Plant Area
- 3210 square meters
-
Number of Employees
- 69
- Terms of Payment
- LC, T/T, D/P, PayPal, Western Union, Small-amount payment, Money Gram
- International Commercial Terms(Incoterms)
- FOB, EXW, CFR, CIF, DDP, CIP, Others
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Average Lead Time
-
Peak Season Lead Time: 1-3 months
Off Season Lead Time: one month -
Nearest Port
- Shanghai Port; Ningbo Port
-
Minimum Order Quantity
- 1 Set
-
Supply Chain Partners
- 150
Our Production Capability & Technical Expertise
-
Main Products
- Pharmaceutical Filling Line, Cleanroom Project
-
Production Lines
- 6
-
Production Machines
- Welding Machine, Lathe, Milling Machine, Bench Drill
-
QA/QC inspectors
- 3 people
-
Inspection Type for Finished Products
- 100% inspection(Visual inspection & Function inspection)
-
Inspection Method for Finished Products
- Have instructions and uniformly followed
-
Customization Options
- Full Customization, Flexible customization
-
ODM Service Available
- Yes
-
OEM Service Available
- Yes
-
R&D Engineers
- 30 people
-
Traceability of Raw Materials
- Yes
Our Industry Experience & Global Business Record
-
Year of Establishment
- 2014-03-10
-
Export Year
- 12 Years
- Main Markets
- North America, South America, Eastern Europe, Southeast Asia, Africa, Oceania, Mid East, Eastern Asia, Western Europe
-
Repeat Buyers Choice
- 10%~30%
-
Number of Foreign Trading Staff
- 16
-
Overseas Agent/Branch
- No
-
New Products Launched in Last year
- Yes
Our Certifications, Standards & Industry Recognition
-
Product Certification
- CE
-
Cooperated with Fortune 500
- Yes
FAQ
- Does the machine support customization?
- Yes, the machine offers full customization and flexible customization options, including customized filling modes and parameters.
- What is the production capacity of this line?
- The production capacity ranges from 2000 to 30,000 pieces per hour with a pass rate of at least 99.5%.
- Is the machine compliant with GMP standards?
- Yes, it meets GMP validation requirements with full traceability and automatic report generation for IQ, OQ, and PQ.
- What materials are used for liquid contact parts?
- All components contacting the liquid are made of medical-grade stainless steel 316L, validated to ISO 10993 for biocompatibility.
- What is the warranty period?
- The machine comes with a 1-year warranty and includes after-sales services like field installation, commissioning, and training.
- Can the machine handle different syringe sizes?
- Yes, the modular design allows quick changeover between different sizes of syringes and catheters.
- What are the minimum order quantity and lead time?
- The minimum order quantity is 1 set. Lead time is 1 month during off-peak season and 1-3 months during peak season.
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