Pharmaceutical Rapid Fluid Bed Fluidizing Mixing Drying Granulator

Product Description

 

Pharmaceutical Rapid Fluid Bed Fluidizing Mixing Drying Granulator


Shanghai Marya is a leading supplier for a pharmaceutical turnkey project, which including pharmaceutical factory design, R&D, machinery manufacturing, shipment, installation, commissioning, and after-sales services.




Pharmaceutical Rapid Fluid Bed Fluidizing Mixing Drying Granulation Machine Mixer Granulator for Medicine Powder



Working Principle:

The powder granule in vessel (fluid bed) appears in the state of fluidization. It is preheated and mixed with clean and heated air. At the same time the solution of adhesive is sprayed into the container. It makes the particles become granulating that contains adhesive.

Being of unceasing dry through hot air, the moisture in the granulating is evaporated. The process is carried out continuously. Finally it forms ideal, uniform and porous granules.

Application:

Tablets, granules, capsules.

Sugar-free,sugar-less or small-dose granules.

Granules of which the medicine effect will be controlled for slow release.

Instant food and beverage granules.

Chemical granules.

Function feature:

1.The flowability is improved and the dust is reduced, because of the granulator.

2.Because of powder granulating, its solubility is improved.
3.The processes of mixing, granulating, and drying are completed in one step inside the machine.

4.The operation is safe because of the anti-static filter cloth adopted.

5.It's safe for the operator if an explosion takes place because the explosion device is adopted.

6.No dead angle. Therefore the loading and unloading are quick, light, and clean, meet the requirements of GMP.

 

Technical Features Description

 Granulation is the operation of processing materials in the state of powder, melting liquid and aqueous solution into particles of certain shape and size. The preparation process of almost all solid preparations is inseparable from  granulation process. The particles may be finished products, such as granules, or  intermediate products, such as tablets.

 The principle of granulation: the granulation operation makes particles have some corresponding purposes, so as to ensure product quality and smooth progress of production. For example, if particles are products in granules and capsules, the purpose of granulation is not only to improve fluidity, dispersion and adhesion of materials, and to facilitate accurate measurement and protect production environment, but also to ensure the uniform shape and size of particles, beautiful appearance and so on. In the production of tablets, particles are intermediate products, it is not only to improve fluidity to reduce weight difference of tablets, but also to ensure compression formability of particles. There are many different kinds of granulation methods, even if the same prescription, granulating content not only has different shape, size and strength, but also has different disintegration and solubility, resulting in different pesticide effect. Therefore, the suitable granulation method should be selected according to characteristics of the required particles.
 The common granulation methods: wet granulation, one-step granulation, dry granulation and spray granulation.

• The purpose of granulation:

1.   To improve liquidity. Generally speaking, the particle size of particle is larger than one of powder, and the number of particles that can be contacted around each particle is less, so adhesion and agglutination are greatly weakened, thus greatly improving fluidity of material. Although material is solid, but it can be treated as quantitatively as liquid.

2.  To prevent separation of various components. It is prone to segregation when particle size and density of each component of the mixture are different, and segregation can be effectively prevented by granulation after mixing or mixing after granulation.

3.  Prevent dust flying and adhesion on the wall. The dust explosion and adhesion of powder are serious. After granulation, environmental pollution and the loss of raw materials can be prevented, which is beneficial to GMP management.
4.   Adjust packing density to improve solubility  
5.  Improve the uniform transmission of pressure in tablet production;
6.  Easy to take and carry, improve value of commodity.
 

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WHY US?

We can provide Pharmaceutical Turnkey project Service including all the pharmaceutical machineries and clean room projects from designing to construction

We can provide our project according to the international regulations like EU cGMP, USA FDA, WHO GMP, UK MHRA, Australian TGA, etc

We can provide 30 year experience engineer team go give you free Consultation service We Can provide FAT and SAT Service

We can provide DQ,IQ,PQ,OQ documents service

We can provide overseas machine installation and commissioning

We can provide free training service for your employee

We can provide One year guarantee for the machine and project

We can provide 24 hours technical support by email

We can provide our installation team to your country to do the installation 

We can provide user friendly English Software ,user manual and detailed video

You have nothing to worry if you cooperate with us for the pharmaceutical Project 

Looking forward to cooperating with you.

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