Marya IV Large Volume Pharmaceutical Bfs Plastic Ampoule/Bottle Blowing Filling Sealing Machine for Pharmaceutical Plant

• Customization: Available
• After-sales Service: 2 Year Warranty
• Warranty: 2 Year Warranty
• Model NO.: MY-BFS
• Type: Piston Filling Machine
• Automatic Grade: Automatic
• Material Type: Liquid
• Filling Valve Head: Multi-Head
• Feed Cylinder Structure: Multi-Room Feeding
• Dosing Device: Capacity Cup
• Filling Principle: Pressure
• Packaging Container Lifting Structure: Pneumatic Lifting
• Structure: Linear
• Packaging: Bottle
• Packaging Material: Plastic
• Voltage: 380V
• Certification: CE/ISO/GMP
• Precision: High Precision
• Computerized: Computerized
• Package Type: Bottles
• Production Speed: 1000-18000bph
• Moc: Stainless Steel
• Advantages: Aseptic Blowing Filling Sealing
• Transport Package: Wooden
• Specification: can be Customized
• Trademark: Marya
• Origin: Cn
• Production Capacity: 200
• Package Size: 350.00cm * 150.00cm * 180.00cm
• Package Gross Weight: 3500.000kg

Product Description

Marya IV Large Volume Pharmaceutical Bfs Plastic Ampoule/Bottle Blowing Filling Sealing Machine for Pharmaceutical Plant

Product Description

Main Application

Shanghai Pharmaceutical Blow Fill Seal Machine (BFS machine for short) is an advanced technology that integrates molding, filling, and sealing under complete control, which enables liquid to be packaged in polypropylene/high-density & low-density polyethylene plastic bottle, and the whole production process automatically completes the followings in a controlled environment (aseptic environment):

• Extrude plastic particles into plastic preform at high temperatures.
• Then the preform is blown into a container by sterilized and filtered air.
• Filling liquid that has been sterilized and filtered.
• Tight sealing of containers after filling.
• BFS Filling Machine is suitable for liquid filling in pharmaceutical, chemical, and food industries with aseptic or non-aseptic packaging in plastic containers.
  
  
  
  Technical data

  Model	Volume type	Mould Qty	Total Cavities	Filling volume	Production capacity
  HQS series	Small volume	1	16/20/30	0.2-30ml	5400-9000BPH
  		2	24/32/40/60	0.2-30ml	7200-18000BPH
  HQD series	Large volume	1	6/8	50-1000ml	1000-1800BPH
  		2	12/16	50-1000ml	1800-3600BPH

• BFS Machine Working Process 
  

Technical Support

1. With online CIP cleaning / SIP System.
2. Effectively reduce the pollution of human operation, environment, and material.
3. Closed sterile filling system for product safety.
4. Time-pressure filling metering system for high-precision filling.
5. PLC control, HMI operation, with the function of data displaying recording, printing and storage, parameters modification, and setting.
 

Bottle Type

1.This BFS machine can be used for the production of small volume injections, eye drops, oral liquid, ear drops, and other products. The filling range is 0.1ml-20ml, output depends on the filling quantity and mould cavity number.

 

2. This BFS machine can also be used for the production of intravenous injections, cleaning fluid, eye-washing drops, lens care solution, etc. The filling range is 50ml-1L, output depends on the filling volume and mould cavity quantity. 

Performance Features

• The design, MOC, manufacturing, assembly, and debugging of the BFS machine meet the requirements of the new GMP standards for drug production.
• Advanced equipment, unique and reasonable structure, stable and reliable performance.
• Applicable Specification: 0.2ml-1000ml plastic bottle (as per user's requirements).
• Production Capacity: 1000-18000BPH 
• The number of bottles made each time: 1-30 bottles/mold, can be selected based on production capacity.
• Filling Accuracy: ≤ ±1% (according to drug characteristics)
• The BFS machine is integrated with bottle-making, filling, and sealing, with compact structure and occupies a small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
• The plastic particles are plasticized by a low-speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
• Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
•  Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on the man-machine interface.
• High production efficiency, stable product performance, simple and reliable operation, and beautiful appearance.
• For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
• The filling system is accurately calculated by time pressure method with high filling precision, which can meet a filling range of 0.2ml-2000ml to ensure production speed.
• The equipment has black and white sections, the moving parts are isolated in non-clean are(black area), and only the basic components and operations are kept in the clean area(white area), which reduces the area of clean room and the number of particles in the clean room for Shanghai Pharmaceutical BFS Eye Drop Plastic Ampoule Bottle Production Machine
• Automatic in-place cleaning / in-place sterilization function (CIP/SIP) can be realized.
• Configurable online monitoring system for dust particles and plankton bacteria.
• In the process of bottle transfer, the inner surface of the interface is not in contact with parts, which eliminates the production of visible foreign matter.
• To realize fully automatic control and monitor of production process, high precision color touch screen operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation, and other control technology are used.
• The products can be customized according to the actual demand of customers.
  
  
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