Marya Automated RTU Pre-Filled Syringe Production Line for Biopharmaceutical/ Cosmetic Applications

• Customization: Available
• After-sales Service: Video Online, Field Installation
• Warranty: 1 Year
• Model NO.: Marya-AA
• Type: Volumetric Filling Machine
• Automatic Grade: Automatic
• Material Type: Liquid
• Filling Valve Head: Multi-Head
• Feed Cylinder Structure: Multi-Room Feeding
• Dosing Device: Rotor
• Filling Principle: Pressure
• Packaging Container Lifting Structure: Customized
• Structure: Rotary
• Packaging: Syringe
• Packaging Material: Glass or Plastic
• Filling Accuracy: 99%
• Isolator: Optional
• Rejected System: Equipped
• Flow Sensor: Equipped
• CIP/SIP System: Optional
• Industry Computer: Realize Part 11
• Electrical Control Program: Equipped
• Capacity: 50-200PCS/Min
• Pump: Ceramic, Stainless Steel
• Buffer Bin: Optional
• UPS: Optional
• Syringe Sorting System: Optional
• Electric Power: 230V 3 Phase
• Air Velocity: 0.45m/S
• Filling Volume: 5ml-10ml
• Transport Package: Export Wooden Cases
• Specification: 1200*800*1800mm
• Trademark: Marya
• Origin: China
• Production Capacity: 5000
• Package Size: 350.00cm * 200.00cm * 200.00cm
• Package Gross Weight: 300.000kg

Product Description

Marya Automated RTU Pre-Filled Syringe Production Line for
Biopharmaceutical/ Cosmetic Applications

Product Description

Introduction:

       The pre-filled syringe filling and stoppering production line is used for the sterile filling of RTU pre-filled syringe, RTU vial, RTU cartridge, etc., can automatically complete unpacking, filling, stoppering and other process steps, and widely used in pharmaceutical, cosmetic medicine, medical and other industries.

      It can accurately fill small doses of drugs, such as vaccines and biological products, antithrombotic drugs, cosmetic medicine products, etc. into containers to ensure precise dosage.  In addition, it can effectively isolate the equipment from the external environment, prevent drug pollution, improve efficiency in the drug production links, and make the clinical use of drugs more convenient.

Key Features:

• High Precision: Equipped with a high-precision ceramic plunger pump for accurate dosage control.
• Efficiency: Caters to various production needs with capabilities ranging from medium to high-speed operations.
• Sterile Operation: Maintains a sterile environment throughout the filling and stoppering process to prevent contamination.
• Intelligent Control: Features automatic monitoring and easy operation for seamless production.
• Wide Application: Compatible with a variety of drugs and RTU packaging materials.
• Regulatory Compliance: Meets GMP, FDA 21CFR part 11, and other regulatory requirements.
• Easy Integration: Seamlessly integrates with other production line equipment for a complete system.
• Modular Design: Allows for easy upgrades and adaptability to various packaging materials.
• Easy Maintenance: Designed for easy disassembly and cleaning, reducing maintenance costs.
• Flexible Production Modes: Supports single batch and continuous production to meet diverse needs.
• Intelligent Operation: Adjustable filling volume and stoppering depth with individual servo motor control.
• Safety: Includes stopper missing detection and various overload protection alarms.
• Traceability: Records key production data for quality control and traceability.
• Versatile Filling Systems: Offers multiple filling systems to accommodate different liquid characteristics.

 

Optional Configurations:

• Nitrogen Filling System: For antioxidant requirements during filling and storage.
• Vacuum Filling and Stoppering Mode: on-damaging and suitable for various types of rubber stoppers.
• Expandable Laminar Flow: Protects product and packaging under class A clean environment.
• PMS Online Monitoring System: Real-time sterile production environment monitoring with data traceability.
• Online Sterilization Plunger Pump: For CIP/SIP functionality of the filling system.

Technical Specifications:

Feature	Description
Compliance	Meets GMP and FDA standards for pharmaceutical production
Servo Control System	Automated process control for stability and efficiency
Applicable Specification	1ml-20ml vials (customizable based on user requirements)
Filling Range	0.1ml-20ml
Production Capacity	2000-30000 vials per hour
Filling Heads	2-10 (selectable based on production needs)
Filling Pump Options	Metal, peristaltic, ceramic pumps

Advantages:

• Customizable Solutions: Tailor-made configurations to meet specific production needs and product characteristics.
• High-Quality Material Handling: Frictionless transfer of stoppers and protection under laminar flow to prevent contamination.
• Environmentally Friendly: Major transmission parts are servo-driven, located inside the machine frame, precise and pollution-free.
• Advanced Control Technologies: Utilizing high-precision color touch screens, PLC automatic control, and variable frequency speed adjustment for full automatic control and monitoring.

 

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