Shanghai Marya China Supplier Pharmaceutical Vial Bottle Washing Liquid Filling Production Line

• Customization: Available
• After-sales Service: Online Instruction
• Warranty: 1 Year
• Model NO.: MY-01
• Type: Piston Filling Machine
• Automatic Grade: Automatic
• Material Type: Liquid
• Filling Valve Head: Multi-Head
• Feed Cylinder Structure: Multi-Room Feeding
• Dosing Device: Capacity Cup
• Filling Principle: Pressure
• Packaging Container Lifting Structure: Pneumatic Lifting
• Structure: Rotary
• Packaging: Bottle
• Packaging Material: Plastic
• Size: 200*100*100cm
• Function: Filling
• Color: Customized
• Usage: Filling Machine
• Certificaate: ISO
• Transport Package: Customized
• Specification: Customized
• Trademark: Marya
• Origin: China
• Production Capacity: 50000pieces/Year
• Package Size: 100.00cm * 200.00cm * 220.00cm
• Package Gross Weight: 100.000kg

Product Description

Shanghai Marya China supplier pharmaceutical vial bottle washing liquid filling production line

Product Description

Performance Features
The vial filling production line is a high-efficient, accurate and safe filling solution and widely used in pharmaceutical, biotechnology, food, cosmetics and other fields. With a quite mature technology and application, it has passed the long-term testing in the market, and recognized by the industry.

1.Our production line consists of four equipment, namely a vertical ultrasonic bottle washing machine, a hot air circulation sterilization tunnel oven, a vial filling and stoppering machine and a vial capping machine. Our technical team has relevant experience of more than ten years. It has been exported to dozens of countries or regions and widely recognized in the international market.
2.Our equipment is highly automated, and can automatically complete the production process from vial loading, washing, drying, filling and stoppering to capping and discharging. It requires less operators and manual intervention, which can effectively improve the production efficiency of customer factories.
3.With good compatibility, every equipment is applicable for 2ml to 100ml vials by replacing change parts.
4.It has high-quality configuration and excellent stability as we use international first-class electrical brands, such as Siemens, ABB, etc. With stable performance and long service life of functional components, accurate movement of moving parts, interlocking function of upstream and downstream equipment, our equipment has good stability.
5.The equipment design refers to international common standards, such as EUGMP, FDA, cGMP and other industry regulations. 6.All parts of the equipment in contact with products/drugs or clean media are made of stainless steel 316L or medical grade silica gel and the parts not in contact with that are made of SS304 or POM and other clean materials. The software has an audit tracking system with 4-level user access management, and each manual intervention or alarm will be recorded.
7.The production line can be equipped with many optional functions, and be customized and designed according to customer's plant drawings or other needs to a certain extent, which makes our customers more worry-free and satisfied.
 

Technical Parameters
 

Model	KGF4	KGF6	KGF8	KGF10	KGF12	KGF20
Applicable specifications	2~30ml vial bottles
Filling heads	4	6	8	10	12	20
Production capacity	50-100bts/min	80-150bts/min	100-200bts/min	150-300bts/min	200-400bts/min	250-500bts/min
Stoppling qualification rate	>=99%
Laminar air cleanliness	100 grade
Vacuum pumping speed	10m3/h	30m3/h	50m3/h	60m3/h	60m3/h	100m3/h
Power consumption	5kw
Power supply	380V 50Hz

 

Features of ultrasonic vertical bottle washing machine
1.It is also often used for cleaning oral liquid bottles and ampoules besides vials. It is applicable to many sizes and easy to replace change parts.
2.Take the QCL40 bottle washing machine, which is the most widely used and applicable to the most sizes, as an example, it is applicable to 2 to 100ml bottles and its production capacity is 4000 to 9600pcs/h.
3.The multiple cleaning ways ensure the cleanliness of the bottle after cleaning. First, ultrasonic cleaning is adopted to remove the dirt adhered to the vial wall, and then filtered water and air are used to alternately spray and dry the inner and outer walls of the vial for many times, so that the foreign matter in the vial is discharged.
4.The stainless steel conveyor belt is adopted to convey bottles with excellent stability. The way of screw separating bottles and use of rotary table fully ensure the smooth vials feeding and discharging and effectively reduce the broken vial rate.
5.The water and air pipelines used for cleaning are separated, without cross contamination, which complies with GMP regulations.
6.The water temperature for cleaning is maintained at about 50-60ºC. The circulating water tank is equipped with stainless steel heating pipe, which can be set to adjust the circulating water temperature. If the temperature is not raised to the specified value, the equipment gives an alarm and does not start.
7.The 10μm circulating water filter and 0.22μm purified water or WFI filter are used, and the brand is Pall (can be adjusted according to customer requirements).

Technical parameters of QCL40 vertical ultrasonic bottle washing machine

Model	QCL40
Capacity	≥6000 pcs/h calculated by 10ml vials
Voltage	380V, 50Hz
Compressed air pressure	0.6-0.8MPa
Compressed air consumption	About 35-40m³/h
WFI (purified water) consumption	About 0.5-0.7m³/h
Vial breakage rate	<0.05%
Dimensions	About2500x2300x1550mm

 

Features of hot air circulation sterilization tunnel oven
1.The oven adopts the hot air laminar flow to sterilize vials at high temperature for a short time, and it is widely used in drying and depyrogenation of antibiotic vials, oral liquid bottles and ampoules after cleaning.
2.The highest temperature of the heating section can reach 350ºC or more, and the outlet temperature of the cooling section is less than and equal to room temperature +15ºC.
3.The hot air circulation heating mode is adopted to make the internal temperature of each section uniform, which is efficient and energy-saving;
4.With the function of preventing HEPA filter burning at the high-temperature section in case of power failure, making operation safe;
5.The air speed of each section of the oven is controlled by the fan frequency converter, and the system is sensitive and stable in performance.
6.With ultrasonic self-cleaning function of mesh belt, it reduces the labor strength of manual periodic cleaning.
7.The high temperature section adopts multi-channel PID control, modular structure, and has more accurate temperature control.
8.It is equipped with multiple differential pressure gauges and temperature sensors to monitor the differential pressure and temperature of each section in real time, and with multi-channel temperature recorder to print temperature curves in real time. The brands we used are international first-class.
 

Technical parameters of KSZ620/43 hot air circulation sterilization tunnel oven

Model	KSZ620/43
Capacity	≥6000 pcs/h calculated by 10ml vials
Voltage	380V, 50Hz
Fresh air supply	About 2500m³/H
Outlet vial temperature	≤room temperature+15ºC
Sterilization temperature	280ºC-350ºC , adjustable
Speed regulation of mesh belt	100-300mm/min
Vial breakage rate	<0.01%

 

Features of vial filling and stoppering machine
1.The filling machine is the core equipment of the vial production line and widely used in sterile injection, cosmetic medicine, oral liquid, freeze-dried powder and other fields. It can be said that other equipment of the vial production line is equipped for this machine.
2.The machine's construction and materials comply with GMP standards. The parts in direct or indirect contact with the product such as filling needle and stopper hopper are made of stainless steel 316L or medical-grade silica gel, while non-contact parts such as exterior parts and laminar flow supports are made of SS304 or POM.
3.An O-rabs system is equipped, which includes class A laminar flow, glove ports, and interlocking safety doors, and door-opening alarm to restrict operator's operation and access; it also has built-in ports for dust particle, airborne viable bacteria, and air speed detection.
4.The equipment is designed for excellent stability. The high-precision servo motor or speed regulating motor is adopted for the moving parts, which has simple structure, low failure rate and more stable operation.
5.With alarm and shutdown function: in case of abnormal phenomenon in operation, it can give an alarm and stop running in time, display fault point, and record and export various data when fault occurs;
6.We use international first-class electrical brand with long service life and stable performance.
7.The adopted rotary stoppering is stable and high-efficient with fast speed. It also has function of no bottle no stoppering.
8.It has high filling accuracy. The full servo control is adopted for the filling system, the filling volume of each pump can be adjusted independently, and the optional online weighing system can realize the self-calibration of the pump;
9.The ceramic plunger pump used is more wear-resistant. The equal-volume filling principle is adopted to make filling volume adjustment more precise;

Technical parameters of KGS4 vial filling and stoppering machine

Model	KGS4
Capacity	≥7200pcs/h
Voltage	380V, 50Hz
Filling head	4
Filling error	≤±1%
Stoppering success rate	≥99.9%
No bottle no filling rate	≥99.9%
Bottle shortage stop running rate	≥99.9%

Features of capping machine
1.The capping machine is used for the last sealing process of 2 to 100ml vials as the last equipment of the vial filling production line.
2.The machine adopts the way of rotary tracking capping and rolling aluminum cap, which has fast capping speed, high productivity, firm and smooth capping mouth without scratch and high qualified rate.
3.The whole machine adopts modular design, and the mold and parts in contact with product are easy to disassemble and replace. It is also applicable to many vial sizes.
4.It is equipped with O-rabs and class 100 laminar flow hood and can provide local class A environment to protect products. The equipment working environment is recommended for class C or B.
5.With multiple sensors interlocked with the filling machine, it can realize the functions of no bottle no capping, no stopper no capping, no cap alarm, etc.
6.With the cap detection function, uncapped bottles will be rejected.

Technical parameters of ZG capping machine

Model	ZG
Capacity	according to the capacity of the filling machine
Voltage	380V, 50Hz
Power consumption	About 10kw
Capping qualified rate	≥99.9%
Vial breakage rate	<0.05%
Weight	About 1000KG

 

 

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