Marya Pharmaceutical Filling Machinery Sterile Vial Filling Machine with Isolation System

Product Description

Marya  Pharmaceutical Filling Machinery Sterile Vial Filling Machine with Isolation System 

Product Description

Main Applications

The vial liquid filling sealing production line is composed of ultrasonic bottle washing machine, sterilization dryer, filling and stoppering machine, capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, removing heat source, cooling, bottle clear-up, (pre-filling nitrogen), filling, (nitrogen filling), plug clear-up, press plug, cap clear-up, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, also made up production line, which is mainly used in production of vial injection and freeze-dried powder injection in pharmaceutical factory, can be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.

Technical Parameters:

 

Model	KGF4	KGF6	KGF8	KGF10	KGF12	KGF20	KGF24
Applicable specifications	2~30ml vial bottles
Filling heads	4	6	8	10	12	20	24
Production capacity	50-100bts/min	80-150bts/min	100-200bts/min	150-300bts/min	200-400bts/min	250-500bts/min	300-600bts/min
Stoppling qualification rate	>=99%
Laminar air cleanliness	100 grade
Vacuum pumping speed	10m3/h	30m3/h	50m3/h	60m3/h	60m3/h	100m3/h	120m3/h
Power consumption	5kw
Power supply	380V 50Hz

 
One-stop solution system:

Cleaning System

Before filling and sealing steps such as vials, ampoules, syringes, and oral liquid syrup bottles, it is a very critical process step to thoroughly clean the inside and outside of the bottle to remove residues and other pollutants inside and outside the container. This step prevents potentially harmful residues from affecting product and user safety. Marya ultrasonic cleaning system has a wide range of applications. Efficient and hygienic, and cost-effective design solutions, which can assist customers in cleaning various types and specifications of containers. The operation is simple and fast.
 

Significant advantages
Three water and three gas cleaning	ultrasonic cleaning, circulating water, injection water, compressed air spray, etc. Clean the inside and outside of the bottle multiple times to prevent cross-contamination
Save costs	circulating water is recycled and filtered independently to save energy costs
Ergonomic design	easy-to-adjust formats and quick format changes increase operational flexibility

 

 

Drying and Sterilizing System

Marya tunnel oven for drying, sterilizing and depyrogenating containers after washing.
After cleaning vials, ampoules, syringes, oral liquid syrup bottles and other containers, removing residual water droplets on the inner and outer walls of the bottles while sterilizing the containers is also the top priority to ensure product safety. In order to adapt to many different types of glass containers, Marya can provide various types of solutions to efficiently and continuously process all different containers through the preheating section, high temperature sterilization section, and cooling section to meet customer needs.
 

Significant advantages
Fully automated	automatic bottle feeding and bottle discharging without operator intervention, improving operating efficiency
Tunnel hot air circulation	the heat source is evenly distributed, and the depyrogenation effect is good
Customizable	drying and sterilization depyrogenation system can be customized according to customer needs

 

 

Filling System

Marya filling systems are highly customizable to ensure that the filling is done in the way the customer desires. With both flexibility and precision, the servo motor controls the filling pump to position and fill, with fast speed, accurate bottle division, and easy replacement of parts. One system can meet various volume filling needs. The application of high-end technology can be applied to the filling of different products and containers, from water to powder, glass bottles to plastic bottles, all of which can meet the customized requirements of customers.
 

Significant advantages
High-precision filling process	filling accuracy: ≤±1% (determined according to the characteristics of the drug)
Multiple application advantages	can be used stand-alone or in production line
Customizable	RABS/Isolators can be configured according to customer needs

 

 

Capping Sealing System

The capping sealing system is suitable for the sealing production of vials after stoppering. No matter how precise the filling accuracy is, we all need reliable capping to ensure the airtightness of the product, so as to ensure the quality of the product. Marya capping sealing system is suitable for sealing and capping various specifications of vials and oral liquid bottles. It can be adjusted according to the combination of different specifications of bottle stoppers and caps. The operation is convenient and fast, and at the same time, it can be equipped with RABS system to ensure a clean environment, providing different solutions for the different needs of customers;

Significant advantage:
Class 100 clean environment, reducing environmental risks;
Equipped with a dust suction device, it can suck away the aluminum chips generated during capping and reduce environmental risks;
 

 

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