Marya Pharmaceutical Pharmaceutical Vial Bottle Filling Production Line Factory

Product Description

Marya Pharmaceutical Pharmaceutical Vial Bottle Filling Production Line Factory

Product Description

 Introduction
        The vial filling production line is composed of washing machine, tunnel, filling and stoppering machine, capping machine. It can integrate bottle washing, drying, filling, stoppering and capping in one machine, enabling the whole process of liquid preparation production. Each machine can be used separately or in linkage line. The whole line is mainly suitable for the production of vaccines, antibiotics, biopharmaceuticals, chemical pharmaceuticals, blood products, etc.

 

 Core Advantages:

• Sterility assurance: Equipped with A level laminar flow protection system to ensure a class 100 clean environment;
• High-precision filling: Servo-drive can realize ±0.5% high-precision filling, up to 400 pcs/min production capacity;
• Integrated modularization: Compact and stable modular design for fully automated operation;
  Efficient capping: Fully automatic aluminum cover feeding and capping system, with ≥ 99.5% qualified rate and adjustable strength;
• Bottle cleaning: Combines ultrasonic cleaning and high-pressure water jetting, achieving >99.8% cleaning efficiency;
• Inert gas replacement: Nitrogen purging before filling to prevent oxidation and degradation of liquid drugs;
  High flexibility: Supports for vials (2R~100R), suitable for small batch and multi-variety production needs;
• Intelligent control:
  1. Siemens touch screen: Intelligent PLC-based control system with touchscreen operation and data traceability;
  2. Intelligent quality control: Intelligent visual inspection for real-time monitoring of filling/sealing quality, automatic rejection of defective products and full-process traceability.

 Core Technology:

• Layout Design: The whole line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce the risk of cross-contamination and ensure aseptic level;
• Washing Process: Ultrasonic cleaning + compressed air purging to remove particles and microorganisms, complying with pharmacopoeial cleanliness standards;
• Drying & Sterilization: The heat in the hot air circulation tunnel oven is evenly distributed, ensuring effective depyrogenation;
• Filling Process: Supporting the filling of liquids, semi-solids (gel), and high-viscosity formulations (e.g., syrups, suspensions);
• Stoppering Process: High-precision mechanical stoppering with ≥99.5% success rate, leak-proof and contamination-resistant;
• Capping Process: Adopting stable and efficient single knife rolling technology, using mechanical capping device to cover the aluminum cap tightly on the mouth of the vial;
• Inspection Process: It can be equipped with light inspection machine for vials and integrated visual inspection system to monitor the quality of filling and sealing in real time and automatically reject unqualified products.

 

Technical Parameters
 

Specifications	1ml~100ml(2R~100R vial bottles)
Filling Accuracy	≤±0.5%(according to drug characteristics and filling volume)
Various Filling Pumps	glass pump, metal pump, peristaltic pump, ceramic pump
Production Speed	10~400 bottles/min (programmable adjustment)
Production Capacity	1000-24000BPH
Filling Heads	1-10, to be selected according to the output
Capping Qualified Rate	≥99.5%
Power Requirement	380V, 50/60Hz
Internal Environment	Laminar flow air cleanliness level 100

Company Profile