Shanghai Marya Mini Bfs Machine for Pharmaceutical Aseptic Filling

• Customization: Available
• After-sales Service: Free Spare Parts, Video Online; Filed Installation
• Warranty: 1 Year
• Model NO.: MARYA AA
• Automatic Grade: Fully Automatic
• Material Type: Liquid
• Filling Valve Head: Multi-Head
• Feed Cylinder Structure: Multi-Room Feeding
• Dosing Device: Pump
• Filling Principle: Pressure
• Packaging Container Lifting Structure: Servo Motor
• Structure: Linear
• Packaging: Bottle
• Packaging Material: Glass
• Finished Dosage Form: Liquid
• Voltage: 380V
• Filling Nozzle: 10-30
• Application: Chemical, Medical, Food
• Machine Power: 1.8 Kw
• Driven Type: Electric
• Suitable Granule: PP/PE
• Filling Volume: 50-500ml
• Logo Printing: Equipped
• Machine Size: 3500*1500*1800mm
• Certificates: CE/ISO/GMP
• Capacity: 9000/Hr
• Bottle Range: 0.5ml-20ml
• Compressed Air: 0.8MPa
• Noise: No More Than 70dB
• Transport Package: Export Wooden Cases
• Specification: Standard/customized
• Trademark: Marya
• Origin: China
• HS Code: 8409919100
• Production Capacity: 5000pieces/Year
• Package Size: 200.00cm * 150.00cm * 100.00cm
• Package Gross Weight: 300.000kg

Product Description

ISO CE Standards Pharmaceutical Small BFS Machine for Cosmetic or Pharmaceutical Industry

Shanghai Marya Mini BFS Machine for Pharmaceutical Aseptic Filling

 

Product Introduction:
     Elevate your pharmaceutical production with our mini Blow Fill Seal (BFS) machines, designed to meet the stringent standards of the pharmaceutical industry. Our BFS technology ensures aseptic filling of liquids in a controlled environment, delivering unparalleled precision and efficiency.
 

Key Features:

• Compliance: Adheres to the latest GMP and FDA regulations for pharmaceutical manufacturing.
• Versatility: Suitable for a wide range of liquid filling applications in the pharmaceutical, chemical, and food industries.
• Capacity: Capable of producing 1000-18000 bottles per hour, depending on the model and configuration.
• Precision: Accurate filling with a precision of ≤±1%, tailored to the characteristics of the pharmaceutical product.
• Innovative Design: Compact structure reduces clean room space and energy consumption, lowering investment and operational costs.

 

Steps of Blow-Fill-Sealing Process
 

Extruding: A parison (rounded mass of molten glass) produced by extrusion of the homogenous polymer melt is introduced into the mold and the below the die.
Molding: The primary mold closes, sealing the bottom. A mandrel fits into the neck area. Using compressed air, the parison is inflated into a container.
Filling: The precisely measured sterile liquid preparation is then delivered into the container by the mandrel.
Sealing: After the mandrel withdrawal, the head mold closes and eventually forms the necessary seal via a vacuum.
 

Advantages:

• Seamless Integration: The line integrates forming, filling, and sealing processes in one unit, ensuring a continuous workflow.
• High-Quality Construction: Utilizes high-quality materials and components, including 304 stainless steel for the hopper, ensuring durability and reliability.
• Efficient Operation: Advanced servo motor control and real-time feedback mechanisms ensure high production efficiency.
• Customization: Capable of meeting specific customer requirements with tailored solutions.

Performance Features
 

S/N	Item	Description
1	Applied bottle range	0.5 ml-20 ml
2	Capacity	9000 /hour
3	Required compressed air	0.8Mpa, 300L/min
4	Noise	≤70dB
5	Electric capacity	75 kw 50 Hz ac 380 V
6	Diameter of cooling water pipe inlet	Φ15mm
7	Cooling water	3 cubic meters, 8 ºC,2 bar
8	Steam	preparation: 40 kg/h 2 bar, production 15 kg/h
9	Clean water	solution line 1m3, 2.5 bar , 15 minutes  vacuum  of mould: 1m3,  2.5 bar, 60 ºC,15 minutes
10	Net weight	8000 kg
11	Overall size	5260 X2600X3015 (long x wide x high)

• The design, MOC, manufacturing, assembly and debugging of the BFS machine meet the requirements of the new GMP or FDA standards for drug production.
• Advanced equipment, unique and reasonable structure, stable and reliable performance.
• Applicable Specification: 0.2ml-1000ml plastic bottle (as per user's requirements).
• Production Capacity: 1000-18000BPH.
• The number of bottles made each time: 1-30 bottles/mould, can be selected based on production capacity.
• Filling Accuracy: ≤ ±1% (according to drug characteristics)
• The BFS machine is integrated with bottle-making, filling and sealing, with compact structure and occupies small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
• The plastic particles are plasticized by a low speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
• Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
•  Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on man-machine interface.
• High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
• For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
• The filling system is accurately calculated by time pressure method with high filling precision, which can meet filling range of 0.2ml-2000ml to ensure production speed.

Why Choose Our BFS Machines?

• Advanced Technology: Utilizes the latest blow fill seal technology for aseptic filling.
• Customizability: Tailored to meet specific production needs and bottle sizes.
• High Efficiency: Optimized for high-speed production without compromising quality.
• Ease of Operation: User-friendly interface with PLC automatic control and servo motor precision.
• Cleanroom Optimization: Reduces cleanroom space requirements and associated energy costs.
• Hygienic Design: Minimizes the risk of contamination with aseptic filling processes.
• In-Situ Cleaning: Capable of automatic CIP/SIP for continuous hygiene.
• Monitoring Systems: Optional online monitoring for dust particles and airborne bacteria.

Company Information

Shanghai Marya Pharmaceutical Engineering&Project Co., Ltd is a professional Pharmaceutical Turnkey Project Contractor. We have 3 our own factories and more than 30 OEM factories under the quality Control of Shanghai Marya, We have a 30 year experienced professional team for doing the turnkey project from design to construction.

Our Pharmaceutical projects can be done according to international standards. We are not only a manufacturer but also a design and construction company. We can provide much better price and better technical support and service than other companies

We can design and manufacture machines based on Customer' requests, Your satisfaction is our top priority.
With 30 years of the experienced professional design team and construction team. Under the support of our factory, We can provide customers with high efficiency and quality in the project, save your time and cost.

NoISO CE Standards Pharmaceutical Small BFS Machine for Cosmetic or Pharmaceutical Industry