| Customization: | Available |
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| After-sales Service: | Online Instruction |
| Warranty: | 1 Year |
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Marya China pharmaceutical glass ampoule liquid filling machine for cosmetic beauty industry
Ampoule filling production line is composed of ultrasonic bottle washing machine, dryer sterilizer and ampoule filling and sealing machine. It can complete spraying water, ultrasonic cleaning, air & water flushing of inner and outer wall of ampoule bottle, preheating, drying and sterilization, heat source removing, cooling, (nitrogen pre-filling), filling, (nitrogen post-filling), ampoule sealing and other complex functions, realizing automatic production of the whole process. Each machine can be used separately or in linkage line. The whole line is mainly used for ampoule injections filling in pharmaceutical factories and the general type can also be used for antibiotic vial injection filling or powder filling.
performance features
1.The whole ampule bottle filling and sealing line meets new GMP requirements, and the cleaning effect meets the new pharmacopoeia standards and requirements.
2.The whole glass ampoule filling machine can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level.
3.Applicable specification: 1ml-20ml ampoule (as per user's requirement)
4.Production Capacity: 12000-36000BPH
5.Number of filling head: 2-20, to be selected according to output
6.Filling Accuracy: ≤ ±1% (according to drug characteristics)
7.Glass ampoule filling machine can choose various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;
8.Compact and simple structure, occupies less area;
9.Stable product performance, easy and reliable operation, beautiful appearance;
10.High degree of automation, fewer operators required;
11.Various sealing gas supply methods such as natural gas or hydrogen and oxygen gas;
12.Optional real-time display and printing system of sterilization temperature;
13.The maximum sterilization temperature of hot air circulation tunnel oven is 350ºC;
14.The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good.
15.Optional open-RABS isolation protection system and class 100 laminar flow hood protection;
16.Optional high-performance no-bottle-no-filling function and squeeze stop function;
17.The filling machine can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.).
18.Full-line linkage control and operation function ;
19. To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used.
20. Applicable for wide range of bottle specifications, and easy to replace mould.
21.The products can be customized according to customer's actual demand.
Step 1
Ultrasonic washing
It adopts washing technology of 2 water and 2 air on the outer wall and 3 water and 4 air on the inner wall.
6 groups of spraying needles have track washing, spray needles adopts full 316L stainless steel. Servo control system+ Guide sleeve and guide board give accurate position to the spray needle, effectively avoid needle damage caused by mismatch.
WFI and compressed air is intermittent, reduce the consumption.
Step 2
Sterilizing& Drying
The washed bottles enter into sterilizing &drying machine slowly uniformly through mesh belt. Pass through preheating zone, high temperature sterilizing zone, cooling zone gradually.
The moisture exhausting fan discharge the bottle vapor to outdoor, in high temperature zone, the bottles are sterilized about 5 minutes under 300-320ºC. The cooling zone cools the sterilized vials, and finally reach to technological requirement.
The whole drying and sterilizing process is operated under real time monitoring.
Step 3
Filling& Sealing
This machine adopts a transmission system of step-by-step with balcony structure.
The machine automatically finishes the whole production process:
Auger conveying---Front nitrogen charging (optional)---Solution filling---Rear nitrogen charging (optional)--- Preheating---Sealing---Counting---Finished products outputting.
| applicable tube size | φ13*75/100mm;φ16*100mm |
| working speed | 15000-18000pcs/hour |
| dosing nethod and accuracy | Anticoagulant: 5 dosing nozzles FMI metering pump, error tolerances±5% based on 20μLCoagulant: 5 dosing nozzles precise ceramic injection pump, error tolerance±6% based on 20μLSodium Citrate: 5 dosing nozzles precise ceramic injection pump, error tolerance±5% based on 100μL |
| drying method | PTC heating with high pressure fan. |
| cap specification | Downward type or upward type cap according to customer's requirements. |
| applicable foam tray | Interlaced type or rectangular type foam tray. |
| power | 380V/50HZ,19KW |
| compressed air | Clean Compressed Air Pressure 0.6-0.8Mpa |
| space occupation | 6300*1200(+1200)*2000 mm (L*W*H) |
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