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| Certification: | CE, GMP, ISO, CE |
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The combination of performance and precision of Marya's cartridge filling and capping line based on the new GMP requirements helps you handle cartridge under optimal conditions. From small batches of special medicine to high-volume production for large-scale distribution, our cartridge filling system reliably supports every step of your production cycle.
Introduction:
The pharmaceutical cartridge filling machine is composed of an ultrasonic bottle washing machine, air-drying and silicone oil spraying integrated machine, tunnel sterilizing dryer and cartridge stoppering filling and capping machine. It can complete the complex functions of spraying water, ultrasonic cleaning, flushing water/inflating air on the inner and outer walls of bottles, air drying, spraying silicone oil, preheating, drying and sterilization, heat removal, cooling, adding bottom stopper, filling, capping and sealing, etc., and realize the automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for the cartridge injection production under aseptic conditions in pharmaceutical industry.
Application:
Marya's cartridge filling machine is mainly used in the field of biomedicine and cosmetics. It is applicable for the filling of vaccines, insulin, antibiotics, interferon, anesthetics, sedatives and hyaluronic acid and other medicine and beauty products. The finished product can also be used in ophthalmology, stomatology, otology, orthopedics, gynecology and other medical industries.
Performance Advantages:
1. Wide range of specifications, large production capacity, high filling accuracy
| Applicable specifications | 1.5-3ml |
| Production capacity | ~8400 bottles/ hour |
| Number of bottom stoppering head | 4 |
| Number of filling heads | 8(filling twice, four at a time) |
| Filling accuracy | up to ±1% |
| Qualification rate of stoppering | ≥99% |
| Qualification rate of capping | ≥99% |
2. Mature, industry-leading high-end technology, stable performance and cost-saving
(1) The filling line adopts a full servo motor system and the parameters can be adjusted on the touch screen;
(2) Adopting advanced electrical control system, stepless speed regulation, complete interlock function, and centralized display of operating parameters;
(3) High degree of automation, automatic data acquisition, and reliably monitoring and recording of data in the key process of production line;
(4) The parts in contact with liquid are all made of 316L stainless steel or silicone, and other surfaces are made of 304 stainless steel or POM (PE);
(5) It has the function of full line linkage and linkage control of front and rear equipment;
(6) Adopting high precision colored touch screen, PLC automatic control, automatic protection, frequency conversion and speed regulation of the host and other control technologies for automatic control and monitoring of production process;
3. Optional functions for tailoring to your needs
(1) Configurable servo motor for controlling the filling pump with high filling accuracy and convenient adjustment;
(2) Configurable CIP/SIP system;
(3) The equipment has compact structure, with a protective cover with glass door, and can be configured with Open-RABS/Close-RABS isolation protection system and class 100 air purification laminar flow system;
(4) Configurable vacuum filling system for filling high viscosity products;
(5) According to whether the client's product is toxic or active, it can be configured with a fully enclosed sterile Isolator system;
(6) Configurable glove test system: A pair of thin elastic gloves are usually the only barrier isolating the machine and the operator;
(7) Configurable pallet to ensure the process of cartridge transportation gentle, safe and fast;
4. Marya also offers ready-to-use (RTU) aseptic filling machines for pre-filled syringes, vials and cartridges
As a leading supplier of filling and sealing solutions for nest type syringes, vials and cartridges, Marya has always been at the forefront of pharmaceutical machinery manufacturing. We use modular and space-saving designs to help you streamline pharmaceutical manufacturing process, reduce waste and save cost.
Unlike a cartridge filling line, nest type RTU containers are brought to the filling machine in the cleanroom as single or double bags and unpacked in a semi-or full-process. There are two main methods of transferring nest boxes to the sterile field. The first option is to use an electron beam or H2O2 for external purification.
Marya's filling units can be combined with fully automatic, semi-automatic and manually operated units with the latest features to meet dynamic market demands.
Ready-to-use applications can reduce reliance on bulk procurement and significantly reduce footprint. Marya offers a combination system for nest-box packaging that works extremely well, making the system flexible to use multiple format types on the same model.
The automatic operation of Marya's aseptic RTU nest-box filling machine includes automatic bag removal, automatic tyvec removal, automatic sealing paper removal, and vacuum filling and stoppering to prevent any microbial contamination.
High flexibility, short transmission time and excellent quality ensure our products performance, and our expertise makes your success possible.
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