Marya Automatic Cartridge Filling Line for Pharmaceuticals High Speed Precision Dosing
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Product Highlights
- GMP and FDA Compliance: Fully compliant with GMP, FDA, and 21 CFR Part 11 standards for seamless traceability and sterile filling.
- Full Servo Motor Control: Features a complete servo motor system with touch screen adjustment and stepless speed regulation.
- End-to-End Integration: Integrates filling, leak testing, capping, and labeling into a single compact unit to reduce downtime.
- Versatile Application: Suitable for vaccines, biologics, insulin, cosmetics, and various medical industries like ophthalmology and orthopedics.
- CIP/SIP Compatibility: Equipped with Clean-in-Place and Sterilize-in-Place capabilities for easy maintenance and hygiene.
- Premium Contact Materials: Uses 316L stainless steel or silicone for chemical contact parts to ensure safety and durability.
- Full Customization Options: Offers flexible customization and full customization services to meet specific production needs.
Product Attributes
- Customization
- Available
- After-sales Service
- Video Online, Field Installation
- Warranty
- 1 Year
- Model NO.
- Marya AC
- Type
- Piston Filling Machine
- Automatic Grade
- Fully Automatic
- Material Type
- Liquid
- Filling Valve Head
- Multi-Head
- Feed Cylinder Structure
- Single-Room Feeding
- Dosing Device
- Plunger
- Filling Principle
- Pressure
- Packaging Container Lifting Structure
- Chute Pneumatic Combination Lifting
- Structure
- Linear
- Packaging
- Tank
- Packaging Material
- Aluminum Foil
- PLC Control System
- Equipped
- Frame Material
- Stainless Steel
- Application
- Chemical, Medical, Cosmetic
- Driven Type
- Electric
- Finished Dosage
- Liquid
- Precision
- High Precision
- Computerized
- Computerized
- Isolation
- Open-Rabs or Close-Rabs
- System
- CIP/SIP
- Transport Package
- Export Wooden Cases
- Specification
- 3400*1670*2350mm
- Trademark
- Marya
- Origin
- China
- Production Capacity
- 5000pieces/Year
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Product Description
for Pharmaceuticals High Speed Precision Dosing
The Marya Automatic Cartridge Filling Line is an advanced pharmaceutical packaging solution designed for high-speed, precision dosing of liquid and semi-solid formulations. Engineered to meet GMP and FDA compliance, this fully automated system ensures sterile filling of cartridges, pre-filled syringes, and other parenteral containers with accuracy up to ±1%. Equipped with servo-driven pumps and vision inspection systems, it minimizes human intervention while maximizing throughput (up to 300+ units per minute). The line integrates leak testing, capping, and labeling in a single compact unit, reducing production downtime. Ideal for vaccines, biologics, and high-value injectables, the Marya Filling Line offers easy changeover, CIP/SIP compatibility, and 21 CFR Part 11 data logging for seamless traceability. A reliable choice for pharma manufacturers seeking efficiency, compliance, and scalability.
Marya cartridge filling line is mainly used in the biomedical and cosmetics industry, suitable for the filling and production of vaccines, insulin, antibiotics, interferon, anesthesia and sedation and other drugs and hyaluronic acid and other beauty products. The finished product can also be used in ophthalmology, stomatology, ear, orthopedics, gynecology and other medical industries.
Key Features:
-
Speed & Precision: 300+ units/min, ±1% dosing accuracy.
-
Regulatory Ready: GMP/FDA compliant, 21 CFR Part 11 support.
-
End-to-End Integration: Filling, inspection, capping in one line.
-
Versatility: Handles liquids, viscous drugs, and sterile products.
| Feature | Description |
|---|---|
| GMP and Pharmacopoeia Compliance | The whole cartridge filling line meets the requirements of the new GMP, and the bottle cleaning effect meets the new pharmacopoeia standards and requirements. |
| Control System | This filling line is a full servo motor system control model, and the parameters that need to be adjusted can be adjusted on the touch screen. |
| Electrical Control | An advanced electrical control system is adopted, the operating speed can be steplessly regulated, with complete interlocking function, and the operating parameter display screen is displayed centrally. |
| Tunnel Oven Heat Source | The heat source of the tunnel hot air circulation oven is evenly distributed, and the heat source removal effect is good. |
| Sterilizing Drying Oven Application | The sterilizing drying oven is not only suitable for the drying, disinfection and sterilization of ampoules, vials and cartridge bottles, but also for the drying, disinfection and sterilization of other pharmaceutical glass bottles. |
| Temperature Recording | Automatic recording of temperature recording and curve chart automatic printing. |
| Bottle Moving and Filling Positioning | Using positioning dial to walk bottles (servo motor driven) to walk 4 bottles at a time, filling positioning is accurate. |
| Filling Method | The ceramic rotary valve pump (8 sets) is used to fill in 2 times, the first filling is 50-70%, the second time is full filling, and there is a vacuum pumping needle at the mouth of the bottle filled in the second filling, and the excess little liquid is pumped into the recycling bottle through the pumping needle. |
| Material of Contact Parts | The parts in contact with the chemical solution are 316L stainless steel or silicone, and the rest of the surfaces are 304 stainless steel or POM (PE). |
| Line Linkage | Marya cartridge bottle filling line has the function of full line linkage, and the front and rear equipment linkage control. |
| Control Technologies | The use of high-precision color touch display operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation and other control technologies for the production process automatic control and monitoring. |










About the Supplier
This supplier has been audited by TÜV Rheinland. Verify the report on the official TÜV Rheinland website with ID "MIC-ASR2542074". Items marked "" are certified.
Company Profile
Marya is a professional aseptic filling line manufacturer with turnkey solutions. With 12 years of industry experience, we have independently developed a comprehensive range of filling lines, including cartridge, vial, and pre-filled syringe (PFS) filling lines. In addition, we offer self-developed supporting equipment such as isolators/RABS, solution preparation systems, and water treatment systems, and VHP sterilizers. Our capabilities also extend to providing turnkey solutions for cleanroom projects and complete filling production lines. We have expanded business to over 70 countries worldwide, serving clients covering European, American and other mainstream markets, including renowned pharmaceutical enterprises and official governmental institutions. Centered around professional filling line technology, we are committed to delivering aseptic production lines and solutions that are stable, compliant, and efficient.
Five Things You Should Know About Marya
1 Engineering design
Our experienced engineering team with more than 20 years experience in pharmaceutical production plants, can ensure that process and equipment for your plant is designed and manufactured in the most cost-effective manner with reliable quality to fulfil GMP/FDA/ISO/SGS requirement.
2 Manufacturing Plants
Marya's 3 manufacturing plants for clean room walls, windows, doors and pharmaceutical machinery are all under strict quality management systems certified to ISO 9001 with a focus on continuous quality improvement.
3 Installation & Commissioning
Experienced, professional, high-efficiency and strictly stick to the schedule, our installation engineers and workers team has successfully installed more than 300+ projects in oversea with high customer satisfaction.
4 Proven Experience
Since 2014, Marya has maintained good cooperation relationship with Novartis, US pharma, MSD, NBA (Zimbabwe National Biotechnology Administration), Novo Nordisk, Techno drugs and other internationally renowned top pharmaceutical companies and national government agencies for a long time. So far, we have assisted famous pharmaceutical factories or government agencies in more than 70+ countries of 6 continents including the United States, Britain, Australia, Malaysia, Argentina and Tanzania to build high-grade cleanroom and aseptic preparation filling production lines that meet local requirements and GMP or FDA standards, winning a very good reputation.
5 Continuous Technical Support
Whatever you buy from us, No matter when your project finished, we will provide continuous service on the operation, maintenance, repairing, spare parts supplying improving and upgrading.
About Our Factory & Business Background
-
Business Type
- Manufacturer/Factory & Trading Company
- Address
- No211, North Fute Road, Pudong Area, 200131, Shanghai, China
-
Plant Area
- 3210 square meters
-
Number of Employees
- 69
- Terms of Payment
- LC, T/T, D/P, PayPal, Western Union, Small-amount payment, Money Gram
- International Commercial Terms(Incoterms)
- FOB, EXW, CFR, CIF, DDP, CIP, Others
-
Average Lead Time
-
Peak Season Lead Time: 1-3 months
Off Season Lead Time: one month -
Nearest Port
- Shanghai Port; Ningbo Port
-
Minimum Order Quantity
- 1 Set
-
Supply Chain Partners
- 150
Our Production Capability & Technical Expertise
-
Main Products
- Pharmaceutical Filling Line, Cleanroom Project
-
Production Lines
- 6
-
Production Machines
- Welding Machine, Lathe, Milling Machine, Bench Drill
-
QA/QC inspectors
- 3 people
-
Inspection Type for Finished Products
- 100% inspection(Visual inspection & Function inspection)
-
Inspection Method for Finished Products
- Have instructions and uniformly followed
-
Customization Options
- Full Customization, Flexible customization
-
ODM Service Available
- Yes
-
OEM Service Available
- Yes
-
R&D Engineers
- 30 people
-
Traceability of Raw Materials
- Yes
Our Industry Experience & Global Business Record
-
Year of Establishment
- 2014-03-10
-
Export Year
- 12 Years
- Main Markets
- North America, South America, Eastern Europe, Southeast Asia, Africa, Oceania, Mid East, Eastern Asia, Western Europe
-
Repeat Buyers Choice
- 10%~30%
-
Number of Foreign Trading Staff
- 16
-
Overseas Agent/Branch
- No
-
New Products Launched in Last year
- Yes
Our Certifications, Standards & Industry Recognition
-
Product Certification
- CE
-
Cooperated with Fortune 500
- Yes
FAQ
- What is the maximum production speed?
- The line can achieve up to 300+ units per minute.
- Does the machine support GMP and FDA compliance?
- Yes, the system is engineered to meet GMP and FDA compliance standards.
- What materials are used for parts in contact with the solution?
- Contact parts are made of 316L stainless steel or silicone, while other surfaces use 304 stainless steel or POM.
- Can the machine be customized?
- Yes, full customization and flexible customization options are available.
- What is the minimum order quantity?
- The minimum order quantity is 1 set.
- What is the lead time for production?
- Lead time is one month during off-peak season and 1-3 months during peak season.
- What types of products can this line fill?
- It is suitable for vaccines, insulin, antibiotics, cosmetics, and other liquid or semi-solid pharmaceuticals.
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