Marya GMP Standard Pharmaceutical Syringe Filling Machine for Prefilled Production Line
Pharmaceutical syringe filling machine is mainly used for the unpacking, tearing, filling and pluging of disposable syringes in honeycomb trays in pharmaceutical plants. It's mainly for the production and packaging of various aseptic products such as vaccines, monoclonal antibodies, small molecule heparin, insulin and hyaluronic acid.
Technical Parameter
| Suitable Product Range |
0.1-20ml (change specification parts properly) |
| Power Supply |
380V 50Hz |
| Power |
4.4kw |
| Filling Error |
+/-1% |
| Compress Air Pressure |
0.6~0.8MPa 20m3/h |
| Auto Stoppering Rate |
>=99.5% |
| Single Machine Noise |
<=70dB |
| Weight |
750kg |
| Dimension |
1630X1320X1700(mm) |
Performance Features
- Our entire production line is meticulously designed, crafted, assembled, and commissioned to meet the stringent requirements of the latest GMP regulations.
- The hyaluronic acid filling machine utilizes an advanced servo control system to automate the entire process, including honeycomb tray unpacking, film tearing, conveying, filling, plug feeding, plug filling, and tray output. This electromechanical integration ensures stable operations and a high degree of automation.
- Applications: Suitable for 1ml - 20ml pre-filled syringes (customizable as per user specifications);
- Filling Range: 0.1ml-20ml
- Capacity: 2,000-30,000 bottles per hour (bph)
- Filling Head: Options of 2-10 heads based on capacity requirements;
- Versatile Filling Pump Options: Choose from metal pumps, peristaltic pumps, or ceramic pumps;
- Filling Accuracy: Ensures precision with an accuracy of ≤ ± 1% (depending on the medicine's characteristics).
- Pass Rate: Remarkably high at ≥99.9%
- Servo system combined with cylinder ensures automatic removal and return of syringes from the honeycomb tray;
- Fully automated production control enhanced by intelligent testing devices at core stations;
- No friction between the plunger's contact surface and the drug solution or bottom rail during transport, ensuring the stopper is consistently protected by laminar flow and mitigating contamination risks;
- The primary drive components are servo-driven and located at the machine's lower frame, enabling precise positioning and minimizing environmental pollution;
- Equipped with a servo motor-controlled filling pump, offering exceptional accuracy and ease of adjustment;
- Configurable CIP/SIP system for enhanced filling system maintenance;
- Optional nitrogen filling unit to prevent medicinal solutions from oxidizing;
- Can be outfitted with a vacuum filling system for highly viscous products;
- Configurable with Open-RABS isolation protection and Class 100 air purification laminar flow systems;
- Features a high-performance system with no bottle no filling, no bottle no capping, and linked bottle squeeze stop functions;
- Multiple robotic systems can be integrated for collaborative control technology, fully automating the processes of film tearing, de-lining, filling, plugging, and weighing of pre-filled syringes;
- Automated calibration feature available for precise filling volume adjustments;
- Can be equipped with fully closed aseptic isolation (Isolator) systems and bag-in-bag-out (BIBO) systems if necessary;
- Comprehensive control and monitoring of the production process with high-precision color touchscreen operation, PLC automatic controls, automatic protection features, and mainframe variable frequency speed regulation;
- Customization options available to meet the specific needs of customers.
Project cases & Our Customer
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